{"id":1648,"date":"2021-02-08T11:37:09","date_gmt":"2021-02-08T19:37:09","guid":{"rendered":"http:\/\/mydiabeticsoul.com\/?p=1648"},"modified":"2021-02-08T11:43:23","modified_gmt":"2021-02-08T19:43:23","slug":"let-me-introduce-you-to-the-stem-cellar","status":"publish","type":"post","link":"http:\/\/mydiabeticsoul.com\/?p=1648","title":{"rendered":"Let Me Introduce You To “The Stem Cellar”"},"content":{"rendered":"\n\n\n
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New post on The Stem Cellar<\/strong><\/h2>\n<\/td>\n

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You can\u2019t take it if you don\u2019t make\u00a0it<\/a><\/h2>\n

by Kevin McCormack<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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Biomedical specialist Mamadou Dialio at work in the Cedars-Sinai Biomanufacturing Center. Photo by Cedars-Sinai.<\/figcaption><\/figure>\n<\/div>\n

Following the race to develop a vaccine for COVID-19 has been a crash course in learning how complicated creating a new therapy is. It\u2019s not just the science involved, but the logistics. Coming up with a vaccine that is both safe and effective is difficult enough, but then how do you make enough doses of it to treat hundreds of millions of people around the world?<\/p>\n

That\u2019s a familiar problem for stem cell researchers. As they develop their products they are often able to make enough cells in their own labs. But as they move into clinical trials where they are testing those cells in more and more people, they need to find a new way to make more cells. And, of course, they need to plan ahead, hoping the therapy is approved by the Food and Drug Administration, so they will need to be able to manufacture enough doses to meet the increased demand.<\/p>\n

We saw proof of that planning ahead this week with the news that Cedars-Sinai Medical Center in Los Angeles has opened up a new Biomanufacturing Center<\/a>.<\/p>\n

Dr. Clive Svendsen, executive director of the Cedars-Sinai Board of Governors Regenerative Medicine Institute, said in a news release<\/a>, the Center will manufacture the next generation of drugs and regenerative medicine therapies.<\/p>\n

“The\u00a0Cedars-Sinai Biomanufacturing Center\u00a0leverages our world-class stem-cell expertise, which already serves scores of clients, to provide a much-needed biomanufacturing facility in Southern California. It is revolutionary by virtue of elevating regenerative medicine and its therapeutic possibilities to an entirely new level-repairing the human body.”<\/p>\n

This is no ordinary manufacturing plant. The Center features nine \u201cclean rooms\u201d that are kept free from dust and other contaminants. Everyone working there has to wear protective suits and masks to ensure they don\u2019t bring anything into the clean rooms.<\/p>\n

The Center will specialize in manufacturing induced pluripotent stem cells, or iPSCs. Dhruv Sareen, PhD, executive director of the Biolmanufacturing Center, says iPSCs are cells that can be turned into any other kind of cell in the body.<\/p>\n

“IPSCs are powerful tools for understanding human disease and developing therapies. These cells enable us to truly practice\u00a0precision medicine\u00a0by developing drug treatments tailored to the individual patient or groups of patients with similar genetic profiles.”<\/p>\n

The Biomanufacturing Center is designed to address a critical bottleneck in bringing cell- and gene-based therapies to the clinic.\u00a0After all, developing a therapy is great, but it\u2019s only half the job. Making enough of it to help the people who need it is the other half.<\/p>\n

CIRM is funding Dr. Svendsen\u2019s<\/a> work in developing therapies for ALS and other diseases and disorders.<\/p>\n

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Kevin McCormack<\/a><\/strong> | December 4, 2020 at 11:00 am | Tags: ALS<\/a>, Cedars-Sinai<\/a>, Cedars-Sinai Biomanufacturing Center<\/a>, COVID-19<\/a>, Dhruv Sareen<\/a>, Dr. Clive Svendsen<\/a>, FDA<\/a>, iPSCs<\/a>, Lou Gehrig’s Disease<\/a>, Spinal muscular atrophy<\/a> | Categories: ALS<\/a>, bioengineering<\/a>, Biotechnology<\/a>, California Institute for Regenerative Medicine<\/a>, Cedars-Sinai Medical Center<\/a>, CIRM funded research<\/a>, Clinical Trials<\/a>, Food and Drug Administration<\/a>, Industry News<\/a>, iPS Cells<\/a>, Research News<\/a>, Spinal cord injury<\/a>, Stem cell research<\/a> | URL: https:\/\/wp.me\/p4BBpx-4FF<\/a><\/div>\n\n\n\n
Comment<\/a><\/td>\n\u00a0\u00a0\u00a0See all comments<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n
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New post on The Stem Cellar You can\u2019t take it if you don\u2019t make\u00a0it by Kevin McCormack Biomedical specialist Mamadou Dialio at work in the Cedars-Sinai Biomanufacturing Center. Photo by Cedars-Sinai. Following the race to develop a vaccine for COVID-19 … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1648","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"http:\/\/mydiabeticsoul.com\/index.php?rest_route=\/wp\/v2\/posts\/1648","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/mydiabeticsoul.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/mydiabeticsoul.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/mydiabeticsoul.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/mydiabeticsoul.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1648"}],"version-history":[{"count":2,"href":"http:\/\/mydiabeticsoul.com\/index.php?rest_route=\/wp\/v2\/posts\/1648\/revisions"}],"predecessor-version":[{"id":1650,"href":"http:\/\/mydiabeticsoul.com\/index.php?rest_route=\/wp\/v2\/posts\/1648\/revisions\/1650"}],"wp:attachment":[{"href":"http:\/\/mydiabeticsoul.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1648"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/mydiabeticsoul.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1648"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/mydiabeticsoul.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1648"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}